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Alflorex Original - Daily Gut Health Supplement with Unique Bifidobacterium Longum Bacteria Strain 35624 - Bacterial Cultures - 30 Capsules
PrecisionBiotics

Alflorex Original - Daily Gut Health Supplement with Unique Bifidobacterium Longum Bacteria Strain 35624 - Bacterial Cultures - 30 Capsules

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★4.5 / 5 ★★★★★ on Amazon · 1,600 customer ratings · recorded 27 Jul 2026
4.4/5
BasketLab score Our own assessment, not the Amazon rating · how we score
  • Evidence4.5
  • Value3.5
  • Suitability4.5
  • Transparency5.0

A well-researched single-strain probiotic with an unusually clean, low-FODMAP-friendly formula. You pay a premium for the specific 35624 strain rather than a bigger bacteria count, and for the right buyer that is a fair trade.

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Overview

Alflorex Original is one of the most talked-about gut health supplements in the UK, and its strong 4.5 out of 5 rating across more than 1,600 reviews puts it among the best-reviewed probiotics in its category. What sets it apart from a shelf full of generic multi-strain capsules is its focus: a single, specific bacterial strain that has been studied more than most. Here is what it actually contains, who it tends to suit, and whether it earns its premium price.

At a glance
Strain
Bifidobacterium longum 35624 (formerly B. infantis 35624)
Formula
Single strain, no prebiotic fibre, no added vitamins
Diet
Gluten free, dairy free, lactose free, certified low FODMAP
Storage
No refrigeration needed
Dose
One capsule daily, any time, with or without food
Best known for
IBS: bloating and abdominal discomfort
Rating
4.5 / 5 on Amazon from 1,600+ UK ratings
Read from the label
Capsules in the pack
30
Cost per capsule
80p
Strains named on the label
Bifidobacterium longum Bacter, Bifidobacterium longum family, Bifidobacterium longum 35624
Strain number given
35624

Taken from the wording on the listing itself and the price we track, not from a brand claim about value. How we rank →

What is Alflorex and how does it work?

Alflorex is built around one carefully selected bacterial strain: Bifidobacterium longum 35624, sometimes written as B. infantis 35624. It is exclusive to PrecisionBiotics in the UK, which is why you will not find this exact strain in supermarket own-brand probiotics. Rather than throwing in a dozen strains at a high headline count, Alflorex bets on one well-researched culture.

The idea behind any probiotic is to top up the friendly bacteria in your gut microbiome, which plays a role in digestion and general wellbeing. Alflorex is designed so the live cultures survive stomach acid and reach the gut in good condition, and it needs no refrigeration, which makes daily use and travel simpler than with fridge-stored probiotics.

Bifidobacterium longum 35624, also called B. infantis 35624

If you have searched for this strain you may have found it under two different names, and the confusion is real rather than a mistake on anyone's part. The culture in Alflorex was originally classified as <strong>Bifidobacterium infantis 35624</strong> and is still widely referred to that way in older research papers and by many pharmacists. It was later reclassified as <strong>Bifidobacterium longum subspecies longum 35624</strong>, which is why the current UK packaging says longum.

It is the same organism either way: strain 35624, developed at University College Cork and commercialised by PrecisionBiotics. When you compare products, the number is what identifies it, not the species name in front of it.

This matters when shopping because <strong>35624 is exclusive to PrecisionBiotics products in the UK</strong>. A generic "bifidobacterium" on another label is not the same thing: bifidobacterium is a whole genus containing many strains that behave differently. If a product does not name the exact strain number, you cannot assume you are getting this one.

Ingredients: what is actually in an Alflorex capsule

The formula is deliberately short, which is part of the appeal. Each capsule provides the live <strong>Bifidobacterium longum 35624</strong> culture in a simple carrier, with no unnecessary extras.

<div class="guide-table-wrap"><table class="guide-table"><thead><tr><th>What you get</th><th>Detail</th></tr></thead><tbody><tr><td><strong>Active culture</strong></td><td>Bifidobacterium longum 35624 (formerly B. infantis 35624)</td></tr><tr><td><strong>Pack</strong></td><td>30 capsules, one-month supply at one a day</td></tr><tr><td><strong>Free from</strong></td><td>Gluten, dairy, lactose, soya</td></tr><tr><td><strong>Suitable for</strong></td><td>Vegetarians; low FODMAP diets</td></tr><tr><td><strong>Storage</strong></td><td>No refrigeration needed</td></tr><tr><td><strong>How to take</strong></td><td>One capsule daily, with or without food, any time</td></tr></tbody></table></div>

There is no prebiotic fibre, no blend of extra strains and no added vitamins. That is a design choice: the product is built around one studied culture rather than a long ingredient list, which is also why it suits people on a low FODMAP diet who react badly to prebiotic fibres such as inulin or FOS.

The routine is simple: one small capsule a day, with or without food, at any time. One pack is a one-month supply. As with any supplement, it is worth reading the label, and this is a food supplement rather than a medicine, so it does not replace advice from a doctor.

On allergens and diet: it is gluten free, dairy free and lactose free, and it needs no refrigeration, which is unusual for a live culture and makes it easy to travel with. One small capsule a day, with or without food, at any time. One pack is a one-month supply.

Does Alflorex actually work? What the evidence says

This is the most-asked question about Alflorex and it deserves a straight answer rather than a brochure one.

Strain 35624 is <strong>unusually well studied for a consumer probiotic</strong>. It was developed at University College Cork and has been the subject of published human trials, most of them in irritable bowel syndrome, where several reported improvements in bloating, abdominal discomfort and bowel habit against placebo. That is a genuinely stronger evidence base than most products on the shelf, which typically rely on general claims about the category rather than on their own specific strain.

The honest qualifications: probiotic effects are <strong>strain-specific and person-specific</strong>. Trials report averages, and within any average some people improve markedly and others not at all. Several of the studies were funded by the developer, which is normal in this field and still worth knowing. And no probiotic is a treatment: under UK rules it cannot be sold as treating or curing anything.

So the fair summary is that Alflorex has better evidence behind its specific strain than almost anything else you can buy without a prescription, and that this still does not tell you whether it will work for <em>you</em>. The only way to find that out is a proper trial of it, which brings us to the next point.

IBS, bloating and constipation: what people actually use it for

Most of the research on 35624 sits in <strong>IBS</strong>, and that is where the product is best known. Reported benefits centre on bloating and abdominal discomfort, with bowel habit improving in some participants.

It is also widely used by people following a <strong>low FODMAP diet</strong>, and it carries certification as low FODMAP, which matters because many probiotics use prebiotic fibres such as inulin or FOS that are themselves high FODMAP and can make symptoms worse. Alflorex contains no prebiotic fibre, which is a design decision rather than an omission.

On <strong>constipation</strong> specifically, the picture is more mixed. IBS comes in constipation-predominant, diarrhoea-predominant and mixed forms, and a strain that helps one person's bloating may do little for another's transit time. If constipation is your main symptom rather than bloating, be realistic about what a single-strain probiotic will do, and know that fibre intake, fluid and movement do more for most people than any capsule.

<strong>A line worth naming:</strong> IBS is a diagnosis of exclusion, and symptoms that look like IBS can have other causes. See a GP rather than self-treating if you have blood in your stool, unexplained weight loss, a change in bowel habit lasting more than a few weeks, symptoms starting after age 50, or a family history of bowel cancer or coeliac disease.

Where to buy it in the UK, and what it should cost

Alflorex is sold widely rather than exclusively: <strong>Boots, Sainsbury's, Holland &amp; Barrett, larger Tesco stores, independent pharmacies and Amazon</strong> all stock it, and PrecisionBiotics sells direct.

Prices move around more than you might expect for a single-SKU product, and a 30-capsule pack is the standard unit. Pharmacy and supermarket shelf prices tend to sit at the higher end, while multi-pack and subscription options online are usually where the per-capsule cost drops. Because this is a product people take for months rather than weeks, per-capsule cost is the number that matters rather than the pack price.

The live price on this page is fetched from Amazon when you load it, so it is current rather than something we typed in. It is worth a quick comparison against your local pharmacy, because the gap is occasionally large in either direction.

One thing to check whatever you buy: <strong>35624 is exclusive to PrecisionBiotics products in the UK.</strong> A cheaper capsule listing "bifidobacterium" without the strain number is not the same organism, and strain is what the research is about.

Is Alflorex worth it? Our verdict

At £23.85 for a month, Alflorex is dearer than a basic multi-strain probiotic, and the honest answer is that you are paying for the specific, well-studied 35624 strain and its clean, low FODMAP friendly formula rather than a bigger bacteria count. The 4.5 rating from a large number of reviewers suggests plenty of people feel it works for them, though probiotics are individual and results vary from person to person.

If you want a simple, once-a-day, fridge-free capsule built on a single researched strain, and especially if you follow a low FODMAP diet, Alflorex is a sensible, well-reviewed choice. If you just want the cheapest general probiotic, a budget multi-strain will cost less. If you have ongoing digestive symptoms, speak to your GP or a dietitian rather than relying on a supplement alone.

Key features, as the manufacturer lists them

Taken from the product listing via Amazon's product API. These are the seller's claims, not our test results.

Frequently asked questions

What bacteria strain is in Alflorex?

Alflorex contains Bifidobacterium longum 35624 (also known as B. infantis 35624), a single specific strain that is exclusive to PrecisionBiotics in the UK. It is chosen for how well it has been studied, rather than for a high number of different strains.

What are the ingredients in Alflorex?

Each capsule provides the live Bifidobacterium longum 35624 culture in a clean formula that is gluten free, dairy free, lactose free and soya free, and suitable for vegetarians and low FODMAP diets. It needs no refrigeration and is taken as one capsule a day.

Is Alflorex good for IBS?

Alflorex is popular among people managing IBS-type symptoms and is often mentioned alongside the low FODMAP diet, and its 35624 strain has been the subject of research. That said, it is a food supplement, not a treatment, and responses vary, so if you have ongoing IBS symptoms it is best to speak to your GP or a dietitian.

How long does Alflorex take to work?

The cultures are designed to reach the gut within a few hours of taking a capsule, but any noticeable effect on digestion tends to build over time with daily use. Many reviewers suggest giving it a few weeks of consistent use before judging whether it suits you.

Does Alflorex need to be kept in the fridge?

No. Alflorex is formulated to be shelf stable, so it does not need refrigeration. That makes it convenient for daily use and for taking away with you, unlike some probiotics that must be kept cold.

Where can you buy Alflorex in the UK?

Alflorex is widely available in the UK: on Amazon, from PrecisionBiotics directly, and in many pharmacies and supermarkets including Boots and larger Sainsbury's stores. Prices vary between retailers, so it is worth comparing; the live Amazon price is shown on this page.

Is Alflorex Bifidobacterium infantis or longum 35624?

Both names refer to the same organism. The strain was originally classified as Bifidobacterium infantis 35624 and later reclassified as Bifidobacterium longum subspecies longum 35624, which is what current UK packaging says. The number 35624 is what identifies it, not the species name.

What's in Alflorex?

One live culture, Bifidobacterium longum 35624, in a simple capsule with no added prebiotic fibre, extra strains or vitamins. It is gluten free, dairy free, lactose free and soya free, suitable for vegetarians and for low FODMAP diets, and needs no refrigeration.

What is PrecisionBiotics?

PrecisionBiotics is the company behind Alflorex and the 35624 strain, which was developed from research at University College Cork. In the UK, strain 35624 is exclusive to PrecisionBiotics products, so you will not find the same culture under another brand.

Can I get Bifidobacterium 35624 from another brand?

Not in the UK. Strain 35624 is exclusive to PrecisionBiotics, and a label that just says bifidobacterium is not equivalent, since that genus contains many strains that behave differently. If the exact strain number is not printed, assume it is a different culture.

Does Alflorex actually work?

Strain 35624 is unusually well studied for a consumer probiotic, with published human trials in IBS reporting improvements in bloating and abdominal discomfort against placebo. Probiotic effects are strain-specific and person-specific, so trial averages do not tell you whether it will work for you. Give it four weeks of daily use before judging.

Is Alflorex good for constipation?

The evidence is strongest for bloating and abdominal discomfort rather than constipation specifically. IBS comes in constipation-predominant, diarrhoea-predominant and mixed forms, and a single strain that helps one may do little for another. For constipation, fibre, fluid and movement do more for most people than any capsule.

Is Alflorex any good compared with cheaper probiotics?

It costs more than a basic multi-strain probiotic and what you pay for is the specific researched strain rather than a bigger CFU number. If you want a studied single strain, particularly on a low FODMAP diet, that is a fair trade. If you want the most bacteria per pound, cheaper high-count blends win.

Can I buy Alflorex in Boots or Sainsbury’s?

Yes. It is stocked by Boots, Sainsbury’s, Holland & Barrett, larger Tesco stores, independent pharmacies and Amazon, and sold direct by PrecisionBiotics. Pharmacy and supermarket shelf prices tend to sit at the higher end; multi-packs online are usually cheaper per capsule.

Is Alflorex low FODMAP?

Yes, it is certified low FODMAP, which matters because many probiotics use prebiotic fibres such as inulin or FOS that are themselves high FODMAP and can worsen symptoms. Alflorex contains no prebiotic fibre.

When should I see a GP instead?

If you have blood in your stool, unexplained weight loss, a change in bowel habit lasting more than a few weeks, symptoms starting after age 50, or a family history of bowel cancer or coeliac disease. IBS is a diagnosis of exclusion and other conditions look similar.

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